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Daniel Horton Receives National Institute for Health Award for Research on Pharmacoepidemiology

Daniel Horton, assistant professor in the pharmacoepidemiology program at the Institute for Health and member of the Department of Pediatrics, Robert Wood Johnson Medical School, Rutgers Biomedical and Health Sciences, is the principal investigator of an award totaling $949,430. The project, titled Drugs, Germs, and Joints: Antibiotics, Gut Microbiota, and Juvenile Idiopathic Arthritis, examines what is not well understood about why children develop juvenile idiopathic arthritis. Some evidence suggests that antibiotics and disturbance of human bacterial communities (“the microbiome”) play a role. The project will analyze the complex relationship between antibiotics, infections, and the microbiome in relation to the development and activity of juvenile idiopathic arthritis. New insights into the mechanisms underlying juvenile idiopathic arthritis and the role of antibiotics may ultimately lead to new, less toxic ways of treating, preventing, or even curing these chronic childhood diseases. The project is supported by the National Institutes of Health.



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